Unlike conventional technology that can harvest Mesenchymal stem cells (MSCs) only, Cordlife’s exclusive patented breakthrough technology can isolate and expand not just Mesenchymal Stem Cells (MSCs) but also Epithelial Stem Cells (EpSCs) from your baby’s umbilical cord tissue. With CellOptima™, you can give your family that additional protection coverage that you have always wanted. HealthBaby obtained this technology in 2020 and this technology is only available at Cordlife.


About CellOptima™

More than 20 years ago, bone marrow was found to contain MSC then Wharton’s Jelly from the umbilical cord was found to contain MSC as well. More recently, a team of award-winning doctor and scientist from Singapore made significant inroad in the world with the discovery of two powerful stem cell types, MSC and EC, from cord lining. Together, the Cambridge and Stanford University trained duo developed a unique technology known as CellOptima™, designed to harvest and multiply stem cells from cord lining. This revolutionary discovery subsequently led the team to receive more than 40 patent grants from 40 countries including United States, Europe, China, Singapore and Hong Kong. These patents prohibit anybody other than the patent owner from harvesting stem cells from cord lining. Only HB and CLHK can store EpSC. Other cord banks cannot get EpSC in the future.


CellOptima™ Assurances for you and your Family

Optimal Condition Assurance

Using CellOptima™ proprietary cell biomarker verifi cation, your baby’s cord lining will be tested after 4 weeks of cryopreservation. During this process, sample segments of the frozen cord lining will be thawed and MSC and/or EC will be harvested according to your choice of storage plan. This verifi cation step is important as it helps ensure that your baby’s cord lining has been properly stored and can be used for future medical treatments. The objective of this process is to validate the following:

  • Cell type/s confi rmation using MSC and/or EC biomarkers
  • Cell viability
  • Cell proliferation also known as the ability to multiply further
  • Cord lining sterility


Explant Purity & Dual Source Storage Assurance

If you choose to extract stem cells now from your baby’s cord lining whether MSC, EC or both for long-term storage, you will automatically enjoy complimentary storage of the cord lining in its original unexpanded form. This gives your family double access to both expanded stem cells which are “treatment-ready” as well as unmanipulated cord lining that can be used for multiple treatments and possibly the extraction of other cell types not identifi ed today. In addition to CellOptima™ proprietary cell biomarker verifi cation, the tests below will be done on the expanded stem cells to ensure that they are viable and safe for use.

  • Count of cells
  • Cell sterility testing
  • Endotoxin analysis
  • Mycoplasma analysis


Usability Assurance

Both MSC and EC harvested with CellOptima™ have been used successfully in human clinical applications. This gives you peace of mind knowing that what you are storing today, can really be used in the future to help your family.


Technology Accessibility Assurance

As long as you remain a cord lining client of Cordlife, you are a guaranteed member of Global Cord Registry. As a member, you will have automatic access to CellOptima™ for the isolation and expansion of MSC and/or EC to support medical treatments. This membership is only granted to Cordlife clients in Hong Kong.


What Makes CellOptima™ Special?

CellOptima™is an original invention from Singapore. Patent protection of CellOptima™ has been granted by many countries because the technology is novel, first-of-its-kind and useful. All patents granted CellOptima™ prevents other companies from harvesting stem cells from cord lining. You can refer to following table for the list of clinical trials with stem cells harvested with CellOptima™:



Partner Universities or Research Institutions

Heart restoration and repair
  • National University of Singapore
  • Hamburg University, Heart Centre, Germany
Wound management and burns
  • Shriner's Children's Burns Hospital, United States
  • Chinese University of Hong Kong
  • National Burns Centre, Hanoi, Vietnam
Cornea regeneration
  • Singapore Eye Research Institute, Singapore
  • National Eye Institute, Hanoi, Vietnam
Liver regeneration
  • National University of Singapore
Skin & hair rejuvenation
  • Camden Medical Centre, Singapore
  • BK Clinic, South Korea
  • National Institute of Dermatology, Hanoi, Vietnam
Insulin-producing cells
  • National Cancer Centre, Singapore
  • National University of Singapore
Neuronal differentiation for hearing impairment
  • Stanford University, United States
Bone differentiation, repair and regeneration
  • AO Foundation, Switzerland
  • Keele University, United Kingdom
Hemophilia A
  • National Cancer Centre, Singapore
Human feeder layer for stem cell culture
  • Duke University, United States and National University of Singapore (co-collaboration)

HealthBaby Exclusive Patended Technology

HealthBaby attained H.K. Patented technology exclusively extracting the whole cord tissue as well as the unique processing, storage and culture technologies can fully enhance the quantity and viability of tissue cells after thawing.

Experiments showed that various tissue cells (adipocytes, chondrocytes and vascular endothelial cells) can be differentiated from the cord tissue processed by HealthBaby patented technology. The cell colony number derived was over 20 fold of that derived from non-minced cord tissue segment.



In HK, only Healthbaby has the exclusive cord patent to process and culture stem cells by licensed technology. Our service contract also states the future possibility to culture MSCs from umbilical cord tissue, offering full guarantee to clients. Remember to be aware whether other cord blood banks have patented technology for processing cord tissue. The quality and guaranty of such services are questionable. HealthBaby Consultant


Global First Cord Storage Service

HealthBaby pioneered to adopt the professional MSCs retrieval techniques from The Chinese University of Hong Kong in 2008.32 HealthBaby adopts sealed multi-partition freezing bag for MSCs storage to eradicate cross-contamination. MSCs culturing service conducted by experienced expertise is available upon request.

MSCs become the mainstream research topic for their great potential. Since no matching is required, MSCs can by used the babies, siblings, parents and even the grandparents. Therefore, parents should cryopreserve the primitive MSCs for future use.