BioArchive® System


 
  • Specifically designed for stem cells storage
  • Cleared by U.S. Food and Drug Administration (FDA)
  • Adopted by 129 cord blood banks in 37 countries
  • Adopted by worldwide large blood banks and 90% cord blood banks in Europe, as well as New York Blood Centre which performed most transplants worldwide
  • Provided over 75% stem cell samples of global cord blood transplants17
  • Survival rate is 10% higher than traditional tanks after transplant15
  • Robotic storage and retrieval system
  • Closed system handling, eliminating the TWEs occurred in traditional tanks, which affect stem cells viability for future transplant18
  • Use of liquid nitrogen (stable temperature at -196˚C) as storage media, which is recommended by reports for long-term stem cells storage19
  • Built-in computerized monitoring system with precise storage record. No external equipments needed
  • Liquid nitrogen reservoir can maintain stable temperature for more than 50 days without electricity supply

Adopted by Worldwide Large Blood Banks and HealthBaby

FDA Cleared, never been compulsory recalled 20,21. Worldwide large blood banks implemented the BioArchive system to enhance the efficiency and quality of cord blood storage. In addition, 90% of the cord blood bank in Europe adopted BioArchive® system. It proves that this system is globally well recognized.

HealthBaby Consultant
 

Cell Viability is the Key of Successful Rate of Transplants

Storing cord blood and umbilical cord is a lifetime safeguard for your children and families. No one wants to have chances to use one day, but if it really happens, have you ever thought of low viability of stem cells will let cord blood and umbilical cord lose its functions? HealthBaby introduced BioArchive® liquid nitrogen storage system which is adopted by most of public cord blood bank in globe (including New York Cord Blood Center, Tokyo Cord Blood Bank and worldwide large blood banks), the purpose is to give the best safeguard for parents.

Use of liquid nitrogen (stable temperature at -196°C) as storage media is recommended by reports for long-term stem cells storage19. Only liquid nitrogen can keep stable -196°C amd cord blood stem cells will suspend all physiological activities and remain dormant. On the contrary, other cord blood banks claimed that stem cells can be stored at 135 ℃ for permanent storage while there is no scientific evidence to prove so. And using traditional vapor nitrogen tank will lead to temperature fuctuation resulting from transient exposure to surrounding air while the stem cells are being cryopreserved, taken out, transported and transferred to vapor nitrogen tanks for storage. Vapor Nitrogen combined with TWEs will lead to loss of viability.

HealthBaby Consultant

 

BioArchive® - The Best Stem Cells Storage Quality


 

BioArchive® System

Traditional Tanks

Specificity
  • FDA cleared, specifically designed for stem cells storage
  • No compulsory recall by FDA due to stem cells quality20,21
  • For biological samples storage previously
Storage Media
  • Liquid nitrogen(-196˚C)
  • Stable temperature to maintain optimum stem cells viability22,23
  • Constant temperature, permanent storage for over 1000 years19
  • Liquid nitrogen reservoir can maintain stable temperature for more than 50 days without electricity supply
  • Liquid (Adopted by HealthBaby) / vapor nitrogen
  • The temperate of vapor nitrogen is unstable and may affect the viability of stem cells
Design and Operation
  • Closed design with stable storage temperature
  • Independent access of samples by periscope without affecting others
  • Eradicated TWEs, high stem cells viability guaranteed
  • Built-in 24-hour surveillance system for instant alarm
  • Manual mode to access samples for contingency
  • Contains sample records only, no risk of hacking attacks to client information
  • Open system causing inconsistent temperature inside the tank25
  • Shared compartment, accessing of one sample will also cause others exposed ti great temperature difference18
  • Transient Warming Events (TWEs) may affect stem cells viabilityclarify
  • Manual operation increases the risk of human errors
Controlled Rate Freezing
  • Built-in controlled rate freezer and eradicates TWEs
  • Steady freezing rate at 2.8℃/min for optimal stem cells condition
  • External freezing procedure is required and samples have to experience unnecessary times to temperature differences and prolonged entry period
Transplant Quality
  • Survival rate is 10% higher than traditional tanks after transplant14
  • Provided over 75% samples of successful transplants worldwide
  • No significant increase in survival rate
Global Usage
  • Adopted by over 80% Netcord’s cord blood banks
  • Adopted by most public cord blood banks worldwide(including New York Cord Blood Center, Tokyo Cord Blood Bank and worldwide large blood banks). Since the cord blood samples are for local public use, the quality requirement is much higher than that of private blood bank, to ensure all samples reaching transplant standard
  • Adopted by 60% cord blood banks in developed countries
  • Mainly adopted by private cord blood banks
Cross Contamination
  • No cross contamination record
  • No matter the cord blood stores in liquid nitrogen or vapor nitrogen, a cross-contamination might happen if containers are not airtight. Only sealed containers can eliminate eventual cross contaminations24,25
  • Rumors in market that liquid nitrogen caused cross-contamination is false
  • Reports showed sealed TG compartment molded freezing bags with liquid nitrogen storage can eradicate cross contaminationclarify
  • Traditional tanks have no "Anti-Contamination" function and beware of this misleading term used by other cord blood banks
  • Cross contamination cases happpened25,clarify

 

Transient Warming Events(TWEs) - Reduce Stem Cells Viability and Affect Transplant Quality


TWEs refers to temperature fluctuation resulting from transient exposure to surrounding air while the stem cells are being cryopreserved, taken out, transported and transferred to vapor nitrogen tanks for storage since they must operate in coordination with an external and independent freezing device. Such kind of repetitive temperature fluctuation will finally cause stem cells bursted and even died. Research report states that TWEs will reduce the number of stem cells even though it does not reach the significant level (>5%) in statistics. The fact is that millions of stem cells are lost due to TWEs18. Another report shows that Vapor Nitrogen combined with TWEs can lead to 20% loss of viability26.

 

You may also be interested in...


The Most Accreditations

The Most Accreditations

HealthBaby is the FIRST and ONLY cord blood laboratory in H.K. obtained FACT and HOKLAS accreditations...

Storage Medium

Storage Medium

Irrespective of the expensive costs incurred, HealthBaby persists to use liquid nitrogen as the storage medium to bank cord blood...

AutoXpress System

AutoXpress® System

AutoXpress® system is specifically designed for stem cells harvesting with the highest MNC and TNC recoveries rate in the industry...