At present, Haematopoietic stem cells or HSCs have been used to treat up to 113 diseases and Cord blood is a rich source of HSCs5,6. These treatable diseases include:


Leukemia (Blood Cancer)

  • Acute Lymphoblastic Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Acute Biphenotypic Leukemia
  • Acute Megakaryocytic Leukemia
  • Acute Undifferentiated Leukemia
  • Atypical Chronic Myeloid Leukemia
  • Bilineal Leukemia
  • Biphenotypic Leukemia
  • Chronic Lymphocytic Leukemia (CLL)
  • Chronic Myelogenous Leukemia (CML)
  • Chronic Neutrophilic Leukemia
  • Hemophagocytic Lymphohistiocytosis (HLH)
  • Juvenile Chronic Myelogenous Leukemia (JCML)
  • Hemophagocytic Lymphohistiocytosis (HLH)
  • Juvenile Chronic Myelogenous Leukemia (JCML)
  • Juvenile Myelomonocytic Leukemia (JMML)
  • Mixed Phenotype Acute Leukemia
  • Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
  • Therapy-Related Myelodysplastic Syndromes



Myelodysplastic Syndromes

  • Refractory Anemia
  • Refractory Anemia with Ringed Sideroblasts (Sideroblastic anemia)
  • Refractory Anemia with Excess Blasts
  • Refractory Anemia with Excess Blasts in Transformation
  • Refractory Cytopenia
  • Refractory Cytopenia



  • Anaplastic Large Cell Lymphoma
  • Blastic Nk Cell Lymphoma
  • Composite Lymphoma
  • Follicular Lymphoma
  • Hodgkin’s Lymphoma
  • Mantle Cell Lymphoma
  • Mycosis Fungoides
  • Non-Hodgkin’s Lymphoma (Burkitt’s Lymphoma)
  • Peripheral T-Cell Lymphoma



Other Disorders of Blood Cell Proliferation


  • Aplastic Anemia
  • Congenital Dyserythropoietic Anemia
  • Dyskeratosis Congenita
  • Fanconi Anemia
  • Paroxysmal Nocturnal Hemoglobinuria (PNH)

Inherited Red Cell Abnormalities Red cells

  • Beta Thalassemia Major (aka Cooley’s Anemia)
  • Diamond-Blackfan Anemia
  • Pure Red Cell Aplasia
  • Sickle Cell Disease

Inherited Platelet Abnormalities Platelets

  • Amegakaryocytosis / Congenital Thrombocytopenia
  • Glanzmann Thrombasthenia

Inherited Immune System Disorders: Severe Combined Immunodeficiency

  • Combined Immunodeficiency
  • SCID with Adenosine Deaminase Deficiency (ADA-SCID)
  • SCID which is X-linked
  • SCID with absence of T & B Cells
  • SCID with absence of T Cells, Normal B Cells
  • Omenn Syndrome

Myeloproliferative Disorders

  • Acute Myelofibrosis
  • Agnogenic Myeloid Metaplasia (Myelofibrosis)
  • Blastic Plasmacytoiddendritic Cell Neoplasm
  • Polycythemia Vera
  • Essential Thrombocythemia
  • Myelodysplastic Syndrome
  • Myeloma Multiplex

Phagocyte Disorders

  • Chediak-Higashi Syndrome
  • Chronic Granulomatous Disease
  • Neutrophil Actin Deficiency
  • Reticular Dysgenesis

Bone Marrow Cancers

  • Multiple Myeloma
  • Plasma Cell Leukemia
  • Waldenstrom’s Macroglobulinemia



Transplants for Inherited Disorders of the Immune System & Other Organs

  • Cartilage-Hair Hypoplasia
  • Erythropoietic Porphyria
  • Hermansky-Pudlak Syndrome
  • Pearson’s Syndrome
  • Shwachman-Diamond Syndrome
  • Systemic Mastocytosis



Transplants for Inherited Metabolic Disorders

Mucopolysaccharidosis (MPS) Storage Diseases

  • Hurler Syndrome (MPS-IH)
  • Scheie Syndrome (MPS-IS)
  • Hunter Syndrome (MPS-II)
  • Sanfilippo Syndrome (MPS-III)
  • Morquio Syndrome (MPS-IV)
  • Maroteaux-Lamy Syndrome (MPS-VI)
  • Sly Syndrome (MPS-VII) (beta-glucuronidase deficiency)
  • Mucolipidosis II (I-cell Disease)

Leukodystrophy Disorders

  • Adrenoleukodystrophy (ALD)
  • Krabbe Disease(Globoid Cell Leukodystrophy)
  • Metachromatic Leukodystrophy
  • Pelizaeus-Merzbacher Disease

Lysosomal Storage Diseases

  • Niemann-Pick Disease
  • Sandhoff Disease
  • Wolman Disease


  • Saa / Amyloidosis

Inherited Metabolic Disorders: Others

  • Lesch-Nyhan Syndrome
  • Osteopetrosis



Solid tumors not originating in the blood or immune system

  • Neuroblastoma
  • Medulloblastoma
  • Retinoblastoma




  • Erdheim Chester Disease
  • Extracranial Malignant Germ Cell Tumors
  • Nijmegen Breakage Syndrome

Document code: EP-013-2022