At present, Haematopoietic stem cells or HSCs have been used to treat up to 113 diseases and Cord blood is a rich source of HSCs5,6. These treatable diseases include:
Leukemias
Acute Leukemia
- Acute Lymphoblastic Leukemia (ALL)
- Acute Myelogenous Leukemia (AML)
- Acute Biphenotypic Leukemia
- Acute Undifferentiated Leukemia
Chronic Leukemia
- Chronic Lymphocytic Leukemia (CLL)
- Chronic Myelogenous Leukemia (CML)
- Chronic Myelomonocytic Leukemia
- Juvenile Chronic Myelogenous Leukemia (JCML)
- Juvenile Myelomonocytic Leukemia (JMML)
Myelodysplastic Syndromes
- Refractory Anemia (RA)
- Refractory Anemia with Ringed Sideroblasts (RARS)
- Refractory Anemia with Excess Blasts (RAEB)
- Refractory Anemia with Excess Blasts in Transformation (RAEB-T)
- Chronic Myelomonocytic Leukemia (CMML)
Leukemia, Unspecified
Lymphomas
- Hodgkin's Lymphoma
- Non-Hodgkin's Lymphoma (Burkitt's Lymphoma)
- Autoimmune Lymphoproliferative Disease
- Lymphoma, Unspecified
Other Disorders of Blood Cell Proliferation
Bone Marrow Failure Syndromes
- Congenital Dyserythropoietic Anemia
- Dyskeratosis Congenita
- Fanconi's Anemia
- Paroxysmal Nocturnal Hemoglobinuria (PNH)
- Shwachman-Diamond Syndrome
- Severe Aplastic Anemia, Unspecified
- Sideroblastic Anemia
- Aplastic Anemia
Inherited Red Cell (Erythrocyte) Abnormalities
- Thalassemia
- Beta Thalassemia Major/ Cooley's Anemia
- Diamond-Blackfan anemia
- Pure Red Cell Aplasia
- Sickle Cell Disease
Inherited Platelet Abnormalities
- Amegakaryocytosis / Congenital Thrombocytopenia
- Glanzmann Thrombasthenia
Inherited Immune System Disorders-Severe Combined Immunideficiency (SCID)
- SCID with Adenosine Deaminase Deficiency (ADA-SCID)
- SCID which is X-linked
- SCID with Absence of T & B Cells
- SCID with absence of T Cells, Normal B Cells
- Omenn Syndrome
Inherited Immune System Disorders - Neutropenias
- Kostmann Syndrome
- Myelokathexis
- Congenital Neutropenia
Myeloproliferative Disorders
- Acute Myelofibrosis
- Agnogenic Myeloid Metaplasia (Myelofibrosis)
- Polycythemia Vera
- Essential Thrombocythemia
Phagocyte Disorders
- Chediak-Higashi Syndrome
- Chronic Granulomatous Disease
- Neutrophil Actin Deficiency
- Reticular Dysgenesis
Bone Marrow Cancers
- Multiple Myeloma
- Plasma Cell Leukemia
- Waldenstrom's Macroglobulinemia
Disorders of Cell Proliferation
- Familial Erythrophagocytic Lymphistiocytosis
- Hemophagocytic Syndrome
- Hemophagocytic Lymphohistiocytosis
- Histiocytosis
- Langerhans Cell Histiocytosis
Inherited Disorders Effecting the Immune System & Other Organs
- Cartilage-Hair Hypoplasia
- Gunther's Disease / Congenital Erythropoietic Porphyria
- Hermansky-Pudlak Syndrome
- Pearson's Syndrome
- Systemic Mastocytosis
Transplants for Inherited Metabolic Disorders
Mucopolysaccharidoses (MPS) Storage Diseases
- Mucopolysaccharidoses (MPS)
- Hurler's Syndrome (MPS-IH)
- Hurler-Scheie Disease (MPS-IS)
- Hunter's Syndrome (MPS-II)
- Sanfilippo Syndrome (MPS-III)
- Morquio Syndrome (MPS-IV)
- Maroteaux-Lamy Syndrome (MPS-VI)
- Sly Syndrome, Beta-Glucuronidase Deficiency (MPS-VII)
- Mucolipidosis II (I-cell Disease)
Leukodystrophy Disorders
- Adrenoleukodystrophy (ALD) / Adrenomyeloneuropathy (AMN)
- Krabbe Disease (Globoid Cell Leukodystrophy)
- Metachromatic Leukodystrophy
- Pelizaeus-Merzbacher Disease
Lysosomal Storage Diseases
- Gaucher Disease
- Niemann-Pick Disease
- Sandhoff Disease
- Tay-Sachs Disease
- Wolman Disease
Metabolic / Storage Diseases
- Alpha Mannosidosis
- Amyloidosis
- Aspartylglucosaminuria
- Austin's Disease (Multiple Sulfatase Deficiency)
- Fucosidosis
- Gangliosidosis
- Infantile Ceroid Lipofucoscinosis
- Neiman-Pick Disease
- Sialidosis
Inheritied Metabolic Disorders - Others
- Lesch-Nyhan Syndrome
- Osteopetrosis
Solid Tumors not Originating in the Blood or Immune System
- Breast Cancer
- Medulloblastoma
- Neuroblastoma
- Retinoblastoma
- Other Malignancy
Miscellaneous
- Epidermolysis Bullosa