Cord Blood |
Umbilical Cord |
Bone Marrow | |
|---|---|---|---|
| Sources | Umbilical Cord and Placenta | Umbilical Cord | Bone Marrow |
| Collection | Collect cord blood from the placenta and umbilical cord after the infant is delivered | Cut the umbilical cord into small pieces after cord blood collection | An invasive procedure which requires a general anesthesia. At least 4-6 months preparation, extracting 1L from the rear of the pelvic bone through a series of injections |
| Age of Stem Cells | 0 | 0 | Same age as the donor |
| Main Functions | Cancers Blood-related Diseases Immunity Diseases Metabolic Diseases |
Differentiation: Adipose, Cartilage, Muscle, Skin, Nerve Cells, etc. Aging Diseases: Arthritis, Bone Fractures, etc. Chronic Diseases: Diabetes, Hepatitis, etc. Serious Illnesses: Stroke, Myocardial Infarction, etc. |
Blood-related Diseases |
| Stem Cells Concentration | Highest HSCs | Highest MSCs | Lower HSCs & MSCs |
| Graft-versus-host Disease(GvHD) | Lower chance(None for self transplantation) | Lower(Helps increasing the success rate of HSCs transplants and minimizing GvHD) | GvHD is the main problem after transplantation and can be fatal in up to 40% of patients |
| Side Effect | No | No | Danger and pain of anesthesia |
| Donor's Willingness | No | No | Difficult to find donor |