The MSCs in umbilical cord are able to minimize Graft Versus Host Disease (GvHD) in directed and unrelated allogeneic cord blood transplants. It can be applied to chronic illnesses treatment, regenerative medicines as well as organ and tissue engineering. In addition, At present, there are more than 880 MSCs clinical trials6,7, including stroke, spinal cord, injury, diabetes and bone fractures, etc. Researches of stem cells therapy are growing worldwide, where MSCs become mainstream research topic, the researches mainly focus on malignancy(cancer), neurological, musculoskeletal and cardiovascular diseases, it demonstrates MSCs in umbilical cord can be used quite widely in medical aspect.

MSCs already have the same ability of EpSCs and even more powerful. Researches showed that MSCs can be induced into Induced Pluripotent Stem Cells(iPSCs)10, which have greater differentiation capacity than Epithelial Stem Cells (EpSCs) and it can be directly differentiated into EpSCs11. Thus, MSCs already have the same ability of EpSCs and even more powerful, i.e. formation of various epithelial cells12 and with the same medical application for treating acute burn and diabetic foot etc.

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Storing Epithelial Stem Cells is Unnecessary

Indeed, Epithelia Stem Cells (EpSCs) are mainly used for skin healing with limited function, while MSCs application is much more extensive. Parents are not recommended to keep EpSCs at unreasonable high cost. Moreover, MSCs become mainstream research topic for their great potential, parents should cryopreserve the primitive MSCs for future use.

HealthBaby Consultant

 

Comparison of MSCs Sources


Items

No. of MSCs / 200 million TNCs

Umbilical Cord 600,600 units
Adult Bone Marrow 200 units
Cord Blood 100 units

 

The Variation of MSCs & Against Age


 

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